1、EchelonNeurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.2Confidential. For internal ev3 Inc use only. Do not distribute.以终为始微导管的作用 跟随微导丝到达治疗区域 输送手术器械到达治疗区域 治疗时间中持续发挥作用 安全的撤离Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.3Confidential.

2、 For internal ev3 Inc use only. Do not distribute.Echelon用于输送弹簧圈和Onyx型号: Echelon 10 & 14 直头，45， 90 150cmNeurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.4Confidential. For internal ev3 Inc use only. Do not distribute.Echelon 规格分析EchelonEchelon 10Echelon 14工作长度150

3、cm150 cm外径：近端/远端内径：近端/远端0.017”0.017”最大容纳导丝0.014”0.014”爆破压600 psi600 psi导管容量0.34mL (150cm)0.27mL with Adapter0.34mL (150cm)0.27mL with Adapter2.1F / 1.7F2.4F / 1.9FEchelon10和14唯一不同的就是管身的外径。医生可根据微导管支撑力的不同要求而进行选择。Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.5Confiden

4、tial. For internal ev3 Inc use only. Do not distribute.设计特点 0.017“ 镍钛 渐进性编织密度 InnerGlide超大内腔钢丝材质钢丝编织内衬技术Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.6Confidential. For internal ev3 Inc use only. Do not distribute.1. 钢丝材质镍钛镍钛合金比不锈钢的优势 形状记忆 在受到压力后会回复到原来的形状 = 出色的形状保持

5、能力 临床价值 在长时间的手术中表现卓越的耐久力和稳定性 超强弹性 耐受很大的压力而不变形 临床价值 出色的动脉瘤内的摆动能力 柔软的头端减少损伤，不易从弹簧圈团里拉出Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.7Confidential. For internal ev3 Inc use only. Do not distribute.材质决定出色表现：Echelon vs. Prowler超强的形状保持能力，可以更好的保持内腔的完整性，使装置可以轻松的通过！Fig 2: 用

6、止血钳夹末端轴Prowler-14Echelon-14Fig 1: Echelon-14和 Prowler-14末端轴Fig 3: 夹后的末端轴Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.8Confidential. For internal ev3 Inc use only. Do not distribute.Echelon-14和Prowler-14都是抗打折微导管。它们都可以打成2mm直径的结而不打折。当把结打开后，Echelon-14的形状保持较Prowler-14好

7、。EchelonProwler材质决定出色表现：Echelon vs. Prowler超强的形状保持能力，可以提供更好的支撑，耐受迂曲血管！Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.9Confidential. For internal ev3 Inc use only. Do not distribute.材质决定出色表现：Echelon vs. ProwlerFig 1: Echelon-14和 Prowler-14末端轴Fig 3: 夹后的末端轴Fig 2: 用止血钳夹

8、末端轴内腔的完整可使装置可以轻松的通过！Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.10Confidential. For internal ev3 Inc use only. Do not distribute.材质决定出色表现：Echelon vs. SL-10ECHELONSL-10SL-10ECHELON超强的形状保持能力，可以更好的保持内腔的完整性，使装置可以轻松的通过！Neurovascular Access2009 ev3 Inc. All rights rese

9、rved. Contents are confidential.11Confidential. For internal ev3 Inc use only. Do not distribute.材质决定出色表现：Echelon vs. SL-10SL-10ECHELONSL-10ECHELON超强的形状保持能力，可以更好的保持内腔的完整性，使装置可以轻松的通过！Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.12Confidential. For internal ev3 Inc

10、use only. Do not distribute.预塑形微导管头端的形状保持能力Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.13Confidential. For internal ev3 Inc use only. Do not distribute.2.钢丝编织渐进性编织密度Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.14Confidential. F

11、or internal ev3 Inc use only. Do not distribute.编织方式决定出色表现Distance from Hub (cm)0100120140160Shaft Strength (in-lbs)0.0000.0050.0100.0150.0200.025Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.15Confidential. For internal ev3 Inc use only. Do not distribute.Echelon

12、10 vs. Echelon 14Distance from Hub (cm)0100110120130140150160Stiffness (in-lbs)0.0000.0050.0100.0150.020Echelon-10Echelon-14Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.16Confidential. For internal ev3 Inc use only. Do not distribute.与竞争对手对比Neurovascular Access200

13、9 ev3 Inc. All rights reserved. Contents are confidential.17Confidential. For internal ev3 Inc use only. Do not distribute.PTFE LinerNitinol BraidPebaxInnerGlide 内衬 (Pebax) 在 PTFE及镍钛钢丝层之间应用了InnerGlide 技术的ECHELON ECHELON初始设计3.InnerGlide 内衬技术增加了微导管内表面的光滑度InnerGlide 降低内表面摩擦力，增进器械的推送能力！Neurovascular Acc

14、ess2009 ev3 Inc. All rights reserved. Contents are confidential.18Confidential. For internal ev3 Inc use only. Do not distribute.4. 超大内腔0.017“ Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.19Confidential. For internal ev3 Inc use only. Do not distribute.5. Echelon

15、标记带 高度不透光的标记带 清楚地指示微导管的位置Echelon-14Prowler-14Excel-14近端标记（位于距离远端标记3cm处）Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.20Confidential. For internal ev3 Inc use only. Do not distribute.6. Echelon Fluoro-Safe 标记EchelonFluoro-Safe Marker 当Fluoro-Safe标记进入到导引导管的锁定接头里时，Ech

16、elon的远端正好接近于导引导管的远端（距离头端90cm处）Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.21Confidential. For internal ev3 Inc use only. Do not distribute.临床益处 保护医生，减少推送微导管过程中的射线量 安全Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.22Confidential.

17、For internal ev3 Inc use only. Do not distribute.7. Echelon 微导管锁定接头结构可视性佳-清晰的管口设计提供更佳的可视性易于操作-大的锁定接头更易操作可耐高压-较多的螺纹可以进行高压注射Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.23Confidential. For internal ev3 Inc use only. Do not distribute.8. Echelon 头端预塑形微导管 Echelon预塑形微导

18、管包括45和90两种，都可以再塑形 镍钛合金设计形状保持能力佳头端长度头端形状Echelon-102.5mm45Echelon-105mm90Echelon-142.5mm45Echelon-145mm90Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.24Confidential. For internal ev3 Inc use only. Do not distribute.8. Echelon 头端预塑形微导管保护装置 取出导管头端时先要完全松开头端Neurovascula

19、r Access2009 ev3 Inc. All rights reserved. Contents are confidential.25Confidential. For internal ev3 Inc use only. Do not distribute.预期头端角度Echelon选择0 - 20直头20- 45 45 45- 90 90 90*90 塑形方法插入塑形针芯进入微导管的远端腔弯曲导管的头端到需要的形状，一般2倍于弯曲的角度。将弯曲部分保持在距离蒸汽1英寸，时间不能超过30秒即刻在冷盐水中冷却Neurovascular Access2009 ev3 Inc. All r

20、ights reserved. Contents are confidential.26Confidential. For internal ev3 Inc use only. Do not distribute.想要塑形的角度Catheter to use塑形针角度蒸汽时间O直头NA30”20直头4030”30Echelon 45, 2030”45Echelon 45NA70Echelon 90, 5030”90Echelon 90NA120Echelon 90, 16530”180Echelon 90, 27030”例如，将Echelon 90用塑形针弯曲到165度，30秒蒸汽后为120度

21、EchelonMandrel塑形范例Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.27Confidential. For internal ev3 Inc use only. Do not distribute.Echelon 应用范围动脉瘤输送弹簧圈Echelon 10可以和球囊一起用在6F的导引导管里AVM、AVFEchelon 10可以和Mirage一起用于AVM (30%的直头微导管用于AVM和瘘)Echelon可以用于PVA, micro-spheres, nbca胶和

22、Onyx的输送Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.28Confidential. For internal ev3 Inc use only. Do not distribute.出色表现 0.017“ 镍钛 渐进性编织密度 InnerGlide超大内腔钢丝材质钢丝编织内衬技术Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.29Confidential. F

23、or internal ev3 Inc use only. Do not distribute.竞争对手信息14系统微导管系统微导管J&JJ&JSTRYKERCOVIDIEN COVIDIENTERUMO微导管名称PROWLER 14PROWLER LP-ESEXCELSIOR SL-10ECHELON 10ECHELON 14HEADWAY 17结构不锈钢编织/铂金线圈不锈钢编织/铂金线圈近端到远端都是线圈扁金属丝 镍钛合金编织扁金属丝 镍钛合金编织不锈钢/远端镍钛外径2.3F/ 1.9F2.3F/1.9F 2.4F/1.7F 2.1F/1.7F 2.4F/1.9F2.4F/

24、1.9F内径0.0165”0.0165”0.0165”0.017”0.017”0.017”可用长度150 或 170 cm150 cm150 cm150 cm150 cm150 cm柔软头端长度50 cm5 cm6 cm22 cm5cmn/a亲水涂层亲水亲水亲水亲水亲水亲水内衬PTFE PTFE PTFE PTFE PTFE PTFE 死腔0.35-0.38 cc0.35 ccn/a0.34cc0.34cc0.29 cc额定破裂压300 psi300 psi300 psi250 psi250 psi300 psi头端形状直头, 45, 90 & J直头, 45, 90 & JS

25、traight, 45, 90, J, C & S直头, 45, 90Straight, 45, 90直头,头端标记 2 1 /2 2 2 2 导引导管最小内径0.035”0.035”0.035”0.050”0.050”0.056”导丝最大外径0.014”0.014”0.014”0.014”0.014”0.014”弹簧圈尺寸*最大 0.014”最大0.014”最大0.014”最大 0.014”最大0.014”最大 0.014”直头Rebar微导管Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are con

26、fidential.31Confidential. For internal ev3 Inc use only. Do not distribute.Rebar的主要特点 Rebar微导管是使用加固的不锈钢线圈编织，以达到抗打折和抗椭圆化。 微导管外表面为亲水涂层，表面光滑；内表面为PTFE涂层，降低器械通过的摩擦力 导丝全通过（OTW）的微导管，用于输送弹簧圈，Onyx和支架等。Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.32Confidential. For interna

27、l ev3 Inc use only. Do not distribute.型号和应用内径(英寸)外径(远端/近端，F)长度（cm）应用Rebar100.0152.3/1.7153弹簧圈Onyx（0.27mL )Rebar140.0172.4/1.9153弹簧圈Onyx(0.29mL)可以HD500Rebar180.0212.8/2.3130/153弹簧圈Onyx可以HD500SolitaireABRebar0270.0272.8/2.8130/145SolitaireABNeurovascular Access2009 ev3 Inc. All rights reserved. Conten

28、ts are confidential.33Confidential. For internal ev3 Inc use only. Do not distribute.问题问题微导管用于建立头颈部的血管通路后进行血管造影，药物输送，弹簧圈输送和栓子输送微导管分为全通过型和血流导向型Echelon的产品定位是多用途微导管，Rebar的产品定位是为输送Onyx设计，也用于弹簧圈和其他栓子输送Echelon选用镍钛合金的优势是形状记忆和超强弹性Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidenti

29、al.34Confidential. For internal ev3 Inc use only. Do not distribute.问题问题Echelon的三明治设计是指Pebax（尼龙），镍钛合金和PTFEEchelon预塑形微导管包括45和90两种Echelon 45和90的头端长度分别为2.5mm和5mm。在所有10或14的微导管里最大内径的微导管是EchelonEchelon 主要销售要点镍钛合金使微导管的表现更加完美，出色的预塑形微导管，可用于多种疾病，最佳的临床解决方案Neurovascular Access2009 ev3 Inc. All rights reserved. Contents are confidential.35Confidential. For internal ev3 Inc use only. Do not distribute.问题